28.ESTROGEN CONTRAINDICATED IN

A.THROMBOEMBOLIC EPISODE
B.BREAST ABCESS
C.HYPERTENSION
D.PREMATURE OVARIAN FAILURE

ANS: THROMBOEMBOLIC EPISODE


Contraindications


Absolute contraindications

Undiagnosed vaginal bleeding
Severe liver disease
Pregnancy
Coronary artery disease (CAD)
Venous thrombosis
Well-differentiated and early endometrial cancer (once treatment for the malignancy is complete, is no longer an absolute contraindication.) Progestins alone may relieve symptoms if the patient is unable to tolerate estrogens.

Relative contraindications

Migraine headaches
Personal history of breast cancer
Personal history of ovarian cancer
History of uterine fibroids
Atypical ductal hyperplasia of the breast
Active gallbladder disease (cholangitis, cholecystitis)