Thursday 28 June 2012

117.SINGLE DOSE SUFFICIENT IN WHICH TYPE OF HYPERSENSITIVITY

A.TYPE 1
B.TYPE 2
C.TYPE 3
D.TYPE 4

ANS:TYPE 2


In type II hypersensitivity (or cytotoxic hypersensitivity)the antibodies produced by the immune response bind to antigens on the patient's own cell surfaces. The antigens recognized in this way may either be intrinsic ("self" antigen, innately part of the patient's cells) or extrinsic (adsorbed onto the cells during exposure to some foreign antigen, possibly as part of infection with a pathogen). These cells are recognized by macrophages or dendritic cells, which act as antigen-presenting cells. This causes a B cell response, wherein antibodies are produced against the foreign antigen.

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