75.GENERAL ANESTHETIC WITH LEAST EFFECT ON HEART

A.ETOMIDATE
B.KETAMINE
C.THIOPENTONE
D.

ANS:ETOMIDATE

	Heart Rate	Heart Rhythm	Contractility
Propofol	no significant change to decreases at higher doses	little effect, potential benefit in slowing heart rate in some fast arrythmias	little effect to ability to decrease cardiac output at higher doses
Pentothal	increases by 10-40%	potential disruption, prolong QT interval	decreases cardiac output
Etomidate	mimimal effect	minimal effect	minimal effect
Ketamine	increases	no specific changes	increases
Fentanyl	decreases	variable, but overall may prevent some arrhythmias	little change to mild increase
Morphine	decreases	variable, but overall may prevent some arrhythmias	uncertain, may be similar to fentanyl
Succinylcholine	variable, usually decreases especially at usual doses and after a second dose	increases likelihood of several kinds of arrhythmias	decreases at usual doses
Halothane	no change to little change	increases likelihood of arrythmias	decreases
Isofllurane	decreases	potential changes, but of unknown significance	decreases
Sevoflurane	decreases	potential changes, but of unknown significance	decreases