Wednesday, 20 June 2012

35.SYSTEMIC ANTIFUNGAL USED IN VULVOVAGINAL CANDIDIASIS

A.FLUCOBAZOLE
B.NYSTATIN
C.GRISEOFULVIN
D.COTRIMAZOLE

ANS:FLUCONAZOLE

Vulvovaginal candidiasis (VVC) can be managed with either topical antifungal agents or a single dose of oral fluconazole. A single dose of oral fluconazole (150 mg) in acute episodes of VVC has been shown to yield clinical and microbiological efficacy as good as or better than topical antifungal agents. A small percentage (< 5%) of women experience chronic recurrent VVC infections, which often require long-term or prophylactic oral azole therapy for control. In such patients, the recommended regimen includes fluconazole 150 mg every other day for 3 doses, followed by weekly fluconazole 150-200 mg for 6 months

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