171.PTH RELEASING TUMOR IS

A.SMALL CELL CA OF LUNG
B.SQUAMOUS CELL CA OF LUNG
C.CLEAR CELL CA
D.

ANS:SQUAMOUS CELL CA OF LUNG


Squamous Cell Lung Cancer
This type of lung cancer commonly develops from the bronchus -- a branch of the main airway to the lungs, and with further growth, this cancer invades the lungs; it releases PTHrP, a protein that behaves like the parathyroid hormone. The parathyroid hormone is released by the parathyroid glands; they promote the increased breakdown of bone to release calcium into the blood. Increase PTHrP release from squamous cell cancer of the lungs, results in hypercalcemia, or high blood calcium.

Small Cell Lung Cancer
Small cell lung cancer is the most aggressive type of lung cancer; It commonly originates within the lungs. The cancer releases antidiuretic hormone, or ADH, which acts in the kidneys. ADH is normally released when blood volume is low, but with small cell lung cancer, ADH is constantly released. The action of ADH results in the direct reabsorption of water from the kidneys. Increased water reabsorption from the kidneys results in water retention.